INTERVERTEBRAL DISC-ON-A-CHIP AS ADVANCED IN VITRO MODEL FOR MECHANOBIOLOGY RESEARCH AND DRUG TESTING: A REVIEW AND PERSPECTIVE

Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective

Discogenic back pain is one of the most diffused musculoskeletal pathologies and a hurdle to a good quality of life for millions of people.Existing therapeutic options are exclusively directed at reducing symptoms, not at targeting the underlying, still poorly understood, Anti Theft Harness degenerative processes.Common intervertebral disc (IVD) di

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A comparative life cycle assessment of fiber-reinforced polymers as a sustainable reinforcement option in concrete beams

Environmental awareness and the need for sustainable construction inspired researchers and practitioners to explore innovative alternatives that might reduce greenhouse gas emissions and energy use related to excessive structural work.One such alternative is the utilization of Fiber-Reinforced Polymer (FRP) bars as a reinforcement in reinforced con

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Serpens: A Highly Compliant Low-Cost ROS-Based Snake Robot with Series Elastic Actuators, Stereoscopic Vision and a Screw-Less Assembly Mechanism

Snake robot locomotion in a cluttered environment where the snake robot utilises a sensory-perceptual system to perceive the surrounding operational environment for means of propulsion is defined as perception-driven obstacle-aided locomotion (POAL).From a control point of view, achieving POAL with traditional rigidly-actuated robots is challenging

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A randomized control trial to evaluate the effect of local instillation of mitomycin-C at the porta after kasai portoenterostomy in patients of biliary atresia

girls sun hats Background: Kasai portoenterostomy (KPE) is the initial treatment for biliary atresia (BA).Even after initial jaundice clearance, a significant number of children presented with the reappearance of symptoms due to ongoing fibrosis involving porta and intrahepatic ducts.Mitomycin-C (MMC) is an antifibrotic agent, and the study hypothe

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